Journal of Global Infectious Diseases

BIOGEOCHEMICAL SCIENCES
Year
: 2010  |  Volume : 2  |  Issue : 2  |  Page : 105--108

In Vitro antibacterial activity of ibuprofen and acetaminophen


Ali Abdul Hussein S AL-Janabi 
 Department of Clinical Laboratory, University of Karbala, Collage of Pharmacy, Iraq

Correspondence Address:
Ali Abdul Hussein S AL-Janabi
Department of Clinical Laboratory, University of Karbala, Collage of Pharmacy
Iraq

Background: Ibuprofen and acetaminophen are common chemical agents that have anti-inflammatory, antipyretic, and analgesic activity. Aims: To detect any potential antibacterial effects of ibuprofen and acetaminophen on pathogenic bacteria. Materials and methods: Ibuprofen and acetaminophen were tested for antibacterial activity against seven isolates of bacteria including gram positive bacteria (Staphylococci aureus and Bacillus subtilis) and gram negative bacteria (E. coli, Enterobacter aerogenes, Enterobacter cloacae, Salmonella typhi and Paracoccus yeei). Spectrophotometer assay was applied to determine the antibacterial activities of ibuprofen and acetaminophen. Three controls were included in this study: Ampicilline sodium (20 μg/ml); cefotaxime sodium (20 μg/ml) and chemical free medium. Results: Staphylococcus aureus and Paracoccus yeei were susceptible to lower concentrations of ibuprofen and acetaminophen (MIC=1.25 mg/ml), while two strains of Enterobacter exhibited resistance to these agents. Conclusions: Ibuprofen and acetaminophen showed a potential antibacterial effect on isolated strains of bacteria. They had the same ability to inhibit bacterial growth.


How to cite this article:
AL-Janabi AS. In Vitro antibacterial activity of ibuprofen and acetaminophen.J Global Infect Dis 2010;2:105-108


How to cite this URL:
AL-Janabi AS. In Vitro antibacterial activity of ibuprofen and acetaminophen. J Global Infect Dis [serial online] 2010 [cited 2020 Oct 28 ];2:105-108
Available from: https://www.jgid.org/article.asp?issn=0974-777X;year=2010;volume=2;issue=2;spage=105;epage=108;aulast=AL-Janabi;type=0