Journal of Global Infectious Diseases

CASE REPORT
Year
: 2012  |  Volume : 4  |  Issue : 2  |  Page : 128--131

Multisystem sarcoidosis in a patient on interferon-α therapy for chronic hepatitis C


Bouchra Oudghiri1, Mohammed Benzagmout2, Sad Boujraf3, Faouzi Belahcen4, Adil Ibrahimi1 
1 Department of Hepatogastroenterology, University Hospital of Fez, Morocco
2 Clinical Neurosciences Laboratory, Faculty of Medicine and Pharmacy of Fez; Department of Neurosurgery, University Hospital of Fez, Morocco
3 Clinical Neurosciences Laboratory, Department of Biophysics and Clinical MRI Methods, Faculty of Medicine and Pharmacy of Fez, Morocco
4 Department of Neurosurgery and Neurology, University Hospital of Fez, Morocco

Correspondence Address:
Sad Boujraf
Clinical Neurosciences Laboratory, Department of Biophysics and Clinical MRI Methods, Faculty of Medicine and Pharmacy of Fez
Morocco

Sarcoidosis is a chronic multisystemic granulomatous disease that is triggered by an autoimmune process. Nowadays, this pathology represents a well-recognized but uncommon complication for antiviral treatment in hepatitis C virus (HCV) infection. Herein, we report a remarkable case of 47-year-old woman treated for chronic HCV infection; the patient has developed interferon alfa-induced sarcoidosis involving the central nervous system. The evolution was fatal despite disrupting the antiviral therapy and initiating a high-dose corticotherapy. This complication of interferon alfa treatment was reported in the literature in only one case. Through this case and a review of the literature, we aim to underline the importance of screening for sarcoidosis before and during the follow-up of HCV patients undergoing antiviral therapy.


How to cite this article:
Oudghiri B, Benzagmout M, Boujraf S, Belahcen F, Ibrahimi A. Multisystem sarcoidosis in a patient on interferon-α therapy for chronic hepatitis C.J Global Infect Dis 2012;4:128-131


How to cite this URL:
Oudghiri B, Benzagmout M, Boujraf S, Belahcen F, Ibrahimi A. Multisystem sarcoidosis in a patient on interferon-α therapy for chronic hepatitis C. J Global Infect Dis [serial online] 2012 [cited 2020 Sep 23 ];4:128-131
Available from: http://www.jgid.org/article.asp?issn=0974-777X;year=2012;volume=4;issue=2;spage=128;epage=131;aulast=Oudghiri;type=0